Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
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02-09-2017, 05:43 PM
Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
[Image: scisource_jf0164_custom-5df4a2d7244c4006...00-c85.jpg]


A newly detected type of Klebsiella pneumoniae bacteria (in red) has acquired genes that make it more deadly.

In the past few years, there have been so many "superbugs" appearing in hospitals around the world that we here at Goats and Soda haven't had the time or resources to report on all of them.

But a new type of pneumonia emerging in China seems so important that we dropped what we were doing to write about it.

Doctors in Hangzhou in southeastern China have detected a a type of pneumonia that is both highly drug-resistant and very deadly. It also spreads easily.

The bacterium — a type of Klebsiella pneumoniae — killed five people in an intensive care unit in Hangzhou in 2016, researchers reported Tuesday in the journal Lancet Infectious Diseases.

"This fatal outbreak happened in a brand new hospital with very good hygiene," says microbiologist Sheng Chen, who co-led the study at the Hong Kong Polytechnic University. "Drug-resistant strains shouldn't have appeared so quickly."

The microbe can fight off all drugs available in China, Chen says. "We don't have anything in China to stop it," he says. "There is a drug available in the U.S. that should be effective against it, but we haven't tested it yet."

In the outbreak, the five patients who died were all older than 53. They were all on ventilators after undergoing major surgeries. And they died from severe lung failure, multiorgan failure or septic shock, the researchers found.

When Chen and his team sequenced the microbes found in the infections, they were shocked at what they saw. These bacteria aren't like other multidrug-resistant pneumonia reported before. They are a fusion of two dangerous forms.

In the past three decades, two types of K. pneumoniae have appeared in hospitals. The first is a drug-resistant form, called CRE, which can fight off even the toughest antibiotics. Last January, this type of pneumonia killed a woman in Nevada. That strain resisted 26 antibiotics.

The second type of K. pneumoniae causes a very severe form of the disease and is known as "hypervirulent."

"The disease progresses very fast," Chen says. "It starts in the lungs and then infects other organs, like the liver."

This hypervirulent form — which is widespread across Chinese hospitals — causes more damage to the body than other strains do. It can spread through communities. And it can even sicken young, healthy adults, Chen says.

For years, doctors feared the two types would one day combine. And now that it has happened, scientists around the world need to be on alert for these triple-threat strains, researchers at Rutgers University write in a commentary about the new study.

"Their study describes an alarming evolutionary event," epidemiologists Liang Chen and Barry Kreiswirth write about the emergence of this worrying pneumonia.

"Failure to control its early spread right now, will make a global epidemic of carbapenem-resistant [CRE], hypervirulent K. pneumoniae hard to avoid," the researchers write.

Approval for the new drug in China would help. In the meantime, doctors can stop it from spreading by identifying outbreaks quickly and isolating people.

http://www.npr.org/sections/goatsandsoda...contagious

"Men willingly believe what they wish." -Julius Caesar
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02-09-2017, 08:35 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
I'm old enough to justify getting the pneumonia shot I see advertised at drugstores, (not that it sounds like it would help for this) but have never done it. I've been considering it. I do get the flu shot every year and haven't had the flu in all the years I've gotten the shot. My grown daughter refuses to get the flu shot just swearing it's given her the flu in the past which I think is just a crock of shit and don't hesitate to tell her that.

THIS thread is downright eerily similar to a fiction novel I read a few months ago. Medusa, by Clive Cussler (with Paul Kemprecos). Written in 2009 the plot involves a new virus that starts in China and threatens to set off a world-wide pandemic. Life imitating fiction now, or fiction imitating life, or life imitating art imitating life imitating...

Either way, this thread is scary. Thanks for sharing the info.

Where are we going and why am I in this hand basket?
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02-09-2017, 08:49 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
Well that's disturbing... Sad (Also I coughed right before clicking.)

Need to think of a witty signature.
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02-09-2017, 09:22 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
(02-09-2017 05:43 PM)Kaneda Wrote:  [Image: scisource_jf0164_custom-5df4a2d7244c4006...00-c85.jpg]

The microbe can fight off all drugs available in China, Chen says. "We don't have anything in China to stop it," he says. "There is a drug available in the U.S. that should be effective against it, but we haven't tested it yet."

http://www.npr.org/sections/goatsandsoda...contagious

Consider I've been caring for a patient with resistant Klebsiella on aztreonam - I wonder if that's the drug they don't have in China? He's also on metronidazole, but sure China has that drug. If this doesn't work, and it probably isn't going to, he's fucked.

Also, our isolation is a bit laughable, especially with open visitation and the general public with zero training on contact precautions coming and going at leisure. Hell, we don't even have a thermometer or glucometer in each room...they get to share with everyone else. Doesn't that make you feel all warm and squishy inside? I know all the MRSA, ESBL E. coli and Klebsiella colonies on my skin and in my bed help me sleep at night.

"If there's a single thing that life teaches us, it's that wishing doesn't make it so." - Lev Grossman
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02-09-2017, 11:33 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
(02-09-2017 09:22 PM)Nurse Wrote:  Consider I've been caring for a patient with resistant Klebsiella on aztreonam - I wonder if that's the drug they don't have in China? He's also on metronidazole, but sure China has that drug. If this doesn't work, and it probably isn't going to, he's fucked.

We're all fucked.

#sigh
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03-09-2017, 07:11 AM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
(02-09-2017 08:35 PM)outtathereligioncloset Wrote:  I'm old enough to justify getting the pneumonia shot I see advertised at drugstores, (not that it sounds like it would help for this) but have never done it. I've been considering it. I do get the flu shot every year and haven't had the flu in all the years I've gotten the shot. My grown daughter refuses to get the flu shot just swearing it's given her the flu in the past which I think is just a crock of shit and don't hesitate to tell her that.

THIS thread is downright eerily similar to a fiction novel I read a few months ago. Medusa, by Clive Cussler (with Paul Kemprecos). Written in 2009 the plot involves a new virus that starts in China and threatens to set off a world-wide pandemic. Life imitating fiction now, or fiction imitating life, or life imitating art imitating life imitating...

Either way, this thread is scary. Thanks for sharing the info.

There are two different pneumonia shots and you should get them both - it's an avoidable and unpleasant way to die. They won't help against the above though.

Hospitals are dangerous anymore. Hubby had to have 3 additional operations to remove dead tissue from the infection he got at the hospital. My cleaning lady, who has become a good friend, has been laid up for 3 months now. She went in for an operation on her foot and it got infected. She has been on all sorts of antibiotics since and her foot looks like a football. Soon they will amputate.

We do need to find a way to either sanitize hospitals better, or to find another way to treat.

[Image: dobie.png]Science is the process we've designed to be responsible for generating our best guess as to what the fuck is going on. Girly Man
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03-09-2017, 07:59 AM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
Pneu Pneumonia?
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04-09-2017, 08:09 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
I reiterate:

Shit's fucked.

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04-09-2017, 10:01 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
At least it's perdy.

Insufferable know-it-all.Einstein God has a plan for us. Please stop screwing it up with your prayers.
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05-09-2017, 01:10 PM
RE: Triple Threat: New Pneumonia Is Drug-Resistant, Deadly And Contagious
Time to put my inner germ-a-phobe practices into overdrive. Being a hermit gets more appealing by the day. I wonder if 2020 will ever be real.
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